Juvéderm Voluma™ XC

What is JUVÉDERM VOLUMA™ XC injectable gel?

JUVÉDERM VOLUMA ™ XC injectable gel is the first and only filler FDA-approved to instantly add volume to the cheek area. It gives you a subtle lift, helping to restore contour and a more youthful profile, for up to 2 years, in patients over the age of 21. It’s different than JUVÉDERM ® XC and works on a different area of the face. JUVÉDERM ® XC smoothes out moderate to severe wrinkles and folds around the nose and mouth, like parentheses. JUVÉDERM VOLUMA ™ XC, however, adds volume to the cheek area.

What else should you know about JUVÉDERM VOLUMA ™ XC?

First and only Hyaluronic Acid (HA) filler FDA-approved to instantly add volume to the cheek area, resulting in a subtle lift Clinically proven to last up to 2 years with optimal treatment JUVÉDERM VOLUMA ™ XC is from the makers of the #1 family of fillers After 24 hours, you should be able to resume your normal activities Side effects are moderate and generally last 2 to 4 weeks. Common side effects include temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration, and itching. Hyaluronic Acid (HA) is a naturally occurring, hydrating substance found in your skin. As you age, you start to lose HA, which causes the skin to lose structure and volume. is uniquely formulated to add volume to all 3 areas of the cheek. JUVÉDERM ® is part of the ALLERGAN portfolio of products and this is the JUVÉDERM ® website. For more information BOTOX ® Cosmetic, visit www.botoxcosmetic.com. JUVÉDERM ® XC and JUVÉDERM VOLUMA TM XC Important Information APPROVED USES JUVÉDERM ® XC injectable gel is for injection into areas of facial tissue where moderate to severe facial wrinkles and folds occur to temporarily add volume to the skin, especially around the nose and mouth. JUVÉDERM VOLUMA TM XC injectable gel is for deep injection in the cheek area to correct age-related volume loss in adults over the age of 21.

IMPORTANT SAFETY INFORMATION
Are there any reasons why I should not receive JUVÉDERM ® XC or JUVÉDERM VOLUMA TM XC?

Do not use these products if you have a history of multiple severe allergies or severe allergic reactions (anaphylaxis), or if you are allergic to the proteins (gram-positive bacterial proteins) used to make the hyaluronic acid (HA) in these products. Do not use JUVÉDERM ® XC or JUVÉDERM VOLUMA TM XC if you are allergic to lidocaine. What precautions should my doctor advise me about? The safety of JUVÉDERM ® XC and JUVÉDERM VOLUMA TM XC injectable gels for use during pregnancy or in women who are breastfeeding has not been studied The safety of JUVÉDERM ® XC for use in patients under 18 years and JUVÉDERM VOLUMA TM XC for patients under 35 years or over 65 years has not been studied The safety and effectiveness of JUVÉDERM ® XC for treatment of areas other than facial wrinkles and folds (such as lips) have not been established in clinical studies The safety and effectiveness of JUVÉDERM VOLUMA TM XC for treatment in areas other than the cheek area have not been established in clinical studies The safety of JUVÉDERM ® XC and JUVÉDERM VOLUMA TM XC in patients with a history of excessive scarring (eg, hypertrophic scarring and keloid formations) and pigmentation disorders has not been studied, and use may result in additional scars or changes in pigmentation The safety of JUVÉDERM VOLUMA TM XC in patients with very thin skin in the cheek area and the safety of repeat treatments in patients has not been studied There is a possible risk of inflammation at the treatment site if laser procedures and chemical peeling are performed after treatment Patients who experience skin injury near the site of injection with these products may be at a higher risk for side effects Tell your doctor if you are on therapy used to decrease the body’s immune response (immunosuppressive therapy). Use of these products may result in an increased risk of infection Tell your doctor if you are using medications that can prolong bleeding, such as aspirin, ibuprofen, or other blood thinners, as this may result in increased bruising or bleeding at the injection site Minimize strenuous exercise and exposure to extensive sun or heat within the first 24 hours following treatment with JUVÉDERM VOLUMA TM XC What are possible side effects? For JUVÉDERM ® XC, most side effects are mild or moderate in nature, and last 7 days or less. The most common side effects include temporary injection-site reactions such as: redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. For JUVÉDERM VOLUMA TM XC, side effects are moderate (uncomfortable), and generally last 2 to 4 weeks. The most common side effects include temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration, and itching. As with all skin-injection procedures, there is a risk of infection. To report a side effect with JUVÉDERM ® XC or JUVÉDERM VOLUMA TM XC, please call Allergan Product Surveillance at 1-800-624-4261. For more information, please see the About Safety page at www.juvederm.com or call the Allergan Medical Information line at 1-800-433-8871. JUVÉDERM ® XC and JUVÉDERM VOLUMA TM XC injectable gels are available by prescription only. BOTOX ® Cosmetic Consumer Important Information BOTOX ® Cosmetic (onabotulinumtoxinA) Important Information Approved Uses BOTOX ® Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary). BOTOX ® Cosmetic is a prescription medicine that is injected into the area around the side of the eyes to improve the look of moderate to severe crow’s feet lines in adults for a short period of time (temporary). IMPORTANT SAFETY INFORMATION BOTOX ® Cosmetic may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX ® Cosmetic: Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing. If this happens, do not drive a car, operate machinery, or do other dangerous activities The dose of BOTOX ® Cosmetic is not the same as, or comparable to, another botulinum toxin product. There has not been a confirmed serious case of spread of toxin effect when BOTOX ® Cosmetic has been used at the recommended dose to treat frown lines or crow’s feet lines. Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint. Do not take BOTOX ® Cosmetic if you: are allergic to any of the ingredients in BOTOX ® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such asMyobloc ® (rimabotulinumtoxinB), Dysport ® (abobotulinumtoxinA), or Xeomin ® (incobotulinumtoxinA); have a skin infection at the planned injection site. Tell your doctor about all your muscle or nerve conditions, such as amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease), myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including severe dysphagia (difficulty swallowing) and respiratory compromise (difficulty breathing) from typical doses of BOTOX ® Cosmetic. Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; weakness of forehead muscles, such as trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX ® Cosmetic can harm your unborn baby); are breast-feeding or plan to breast-feed (it is not known if BOTOX ® Cosmetic passes into breast milk). Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. Using BOTOX ® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX ® Cosmetic in the past. Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin, such as Myobloc ® , Dysport ® , or Xeomin ® in the past (be sure your doctor knows exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take antiplatelets (aspirin-like products) or anticoagulants (blood thinners). Other side effects of BOTOX ® Cosmetic include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes. For more information refer to the Medication Guide or talk with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Please see BOTOX ® Cosmetic full Product Information including Boxed Warning and Medication Guide. LATISSE ® (bimatoprost ophthalmic solution) 0.03% Important Information Approved Use LATISSE ® is a prescription treatment for hypotrichosis (inadequate or not enough lashes) to grow eyelashes longer, fuller and darker. IMPORTANT SAFETY INFORMATION If you use/used prescription products for eye pressure problems, use LATISSE ® under doctor care. LATISSE ® may cause increased brown pigmentation of the colored part of the eye which is likely permanent. Eyelid skin darkening may occur and may be reversible. Only apply at the base of the upper eyelashes. DO NOT APPLY to lower lid. Hair may grow on skin that LATISSE ® solution frequently touches. If you have eye problems/surgery, consult your doctor about use of LATISSE ® . Common side effects are itchy and red eyes. If discontinued, lashes will gradually return to their previous appearance. You are encouraged to report negative side effects of prescriptions drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Please click here for full LATISSE ® Product Information. Information about NATRELLE ® The NATRELLE ® Collection of Breast Implants is indicated for females for breast augmentation and breast reconstruction. ©2014 Allergan, Inc. ® and ™ marks owned by Allergan, Inc. JUVÉDERM ® mark owned by Allergan Industrie SAS. Make-A-Wish ® is a registered trademark of Make-A-Wish Foundation America Dress for Success ® is a registered trademark of Dress for Success Worldwide SkinMedica registered trademarks are owned by SkinMedica, Inc. Dysport ® is a registered trademark of Ipsen Biopharm Limited Myobloc ® is a registered trademark of Solstice Neurosciences, Inc Xeomin is a registered trademark of Merz Pharma GmbH & Co. KGaA. Important JUVÉDERM ® Safety Information Glossary Privacy Policy Contact Allergan Site MapAPC10XI13